$MET

Metformin

Discover the story

Discover the story

Metformin

Metformin

What's is Metformin

Metformin, a widely used drug for managing type 2 diabetes, has gained significant attention for its potential longevity benefits based on multiple preclinical and clinical studies. The interest in metformin as a longevity agent stems from its role in modulating pathways linked to aging and chronic diseases.

The mechanisms through which metformin operates are multifaceted, involving modulation of metabolic processes, reduction of inflammation, and potential impacts on cancer biology. One of the primary mechanisms attributed to metformin's effects on longevity is its ability to enhance insulin sensitivity and reduce hyperglycemia. By activating AMP-activated protein kinase (AMPK), metformin promotes cellular energy homeostasis, which is crucial for maintaining metabolic health

Metformin Contract

Metformin Contract

Why Metformin

Why Metformin

Why Metformin

Metformin-Specific Findings of this study that @bryan_johnson Mentioning.

The Study

@bryan_johnson

Mechanistic Insights

For example, metformin scored lower for inflammation-related and brain health−related pathways, as well as metabolic system functions, demonstrating the potential wide-ranging effects of drug treatment on age-associated pathways.

Biomarker Responsiveness

The reduction in epigenetic age was found to be quite significant for biometrics as SystemsAge, PCGrimAge, and PCPhenoAge under metformin treatment. Such changes reflect an impact on the processes of biological aging.

It was described in various physiological systems, reflecting its systemic effects.

Comparison with Other Interventions

Compared to other pharmacological interventions, metformin demonstrated a substantial and consistent decrease in biological age, affirming its potential as a longevity-promoting agent.

Our Team & Our Aim

Our Team & Our Aim

Our Team & Our Aim

Our team of three experienced medical doctors, with a strong track record of publications in high-impact SCI and SCI-Expanded journals, is embarking on an ambitious research project to investigate the longevity benefits of metformin.

Metformin, widely recognized for its efficacy in managing type 2 diabetes, has drawn growing interest for its potential to influence aging and chronic disease pathways. Preclinical and clinical studies suggest that metformin may play a pivotal role in modulating mechanisms associated with aging, opening new avenues for research in longevity science.

As part of this initiative, we are planning a series of animal experiments to explore the mechanisms by which metformin may impact longevity. These studies will help elucidate how metformin modulates biological processes linked to aging and provide critical insights into its therapeutic potential beyond its traditional applications.

Our aim is to contribute meaningful insights to the existing body of knowledge by designing and conducting rigorous studies. Through evidence-based research and scientific collaboration, we strive to advance understanding in this promising field and provide a foundation for future innovations in age-related medicine.

Metformin, widely recognized for its efficacy in managing type 2 diabetes, has drawn growing interest for its potential to influence aging and chronic disease pathways. Preclinical and clinical studies suggest that metformin may play a pivotal role in modulating mechanisms associated with aging, opening new avenues for research in longevity science.

As part of this initiative, we are planning a series of animal experiments to explore the mechanisms by which metformin may impact longevity. These studies will help elucidate how metformin modulates biological processes linked to aging and provide critical insights into its therapeutic potential beyond its traditional applications.

Our aim is to contribute meaningful insights to the existing body of knowledge by designing and conducting rigorous studies. Through evidence-based research and scientific collaboration, we strive to advance understanding in this promising field and provide a foundation for future innovations in age-related medicine.

Metformin Contract

Metformin Contract

Metformin Contract

7w9gX1WBAYs6KnTd5oZdNNDS887YcBo4yScj66dUpump

+3M

Mkt Cap

+2270

Holders

+1,500

Metformin

Metformin

What's is Metformin

Metformin, a widely used drug for managing type 2 diabetes, has gained significant attention for its potential longevity benefits based on multiple preclinical and clinical studies. The interest in metformin as a longevity agent stems from its role in modulating pathways linked to aging and chronic diseases.

The mechanisms through which metformin operates are multifaceted, involving modulation of metabolic processes, reduction of inflammation, and potential impacts on cancer biology. One of the primary mechanisms attributed to metformin's effects on longevity is its ability to enhance insulin sensitivity and reduce hyperglycemia. By activating AMP-activated protein kinase (AMPK), metformin promotes cellular energy homeostasis, which is crucial for maintaining metabolic health

Metformin Contract

Metformin Contract

7w9gX1WBAYs6KnTd5oZdNNDS887YcBo4yScj66dUpump